Sugar acids and derivatives
Apexbio Technology LLC PKH67 Green Fluorescent Cell Linker Kit(Synonyms: PKH67 Cell Labeling Kit, PKH67 Fluorescent Dye Kit, PKH67 Green Fluorescent Cell Dye), 250T.
PKH67 Green Fluorescent Cell Linker Kit is designed for fluorescent labeling of cell membranes The kit utilizes the green fluorescent probe PKH67 a lipophilic dye that integrates stably into lipid regions of the plasma membrane emitting bright green fluorescence Upon cell division PKH67 distributes evenly among progeny cells causing fluorescence intensity to diminish incrementally with cell proliferation Due to its stability low cytotoxicity and minimal staining of adjacent cells PKH67 is widely applied in vitro and in vivo for tracking cell migration localization and monitoring cell proliferation dynamics Additionally PKH67 can be combined with other fluorescent dyes such as PKH26 for multiplex cell-labeling studies
Apexbio Technology LLC PKH26 Red Fluorescent Cell Linker Kit(Synonyms: PKH26 Cell Membrane Dye, PKH26 Fluorescent Cell Labeling Kit), 250T.
PKH26 Red Fluorescent Cell Linker Kit comprises the red fluorescent probe PKH26 designed specifically to label cellular membranes PKH26 integrates stably into lipid regions of cell membranes emitting red fluorescence and enabling clear visualization of cells Due to low cytotoxicity low nonspecific background fluorescence and minimal dye transfer to neighboring unlabeled cells PKH26 has broad utility in tracking cells both in vitro and in vivo Its fluorescence is evenly partitioned between daughter cells during proliferation diminishing with each round of cell division facilitating proliferation assays PKH26 is frequently employed alone or in combination with PKH67 for cell tracking studies and proliferation analyses
Selleck Chemical LLC Heparin sodium S1346-1g
Heparin sodium a sulfated polysaccharide belonging to the family of glycosaminoglycans has numerous important biological activities associated with its interaction with diverse proteins Heparin is used as an anticoagulant primarily through its interaction with AT III by enhancing AT-IIImediated inhibition of blood coagulation factors including thrombin and factor Xa Heparin prevents the induction of autophagy
Medchemexpress LLC Neuraminic acid, N-(2-hydroxyacetyl)- | 1113-83-3 | 99.8% | 1 ML
N-Glycolylneuraminic acid, with chemical formula C11H19NO10 and molecular weight 325.27, is a nonhuman sialic acid molecule. Synthesized in pigs but not in humans, it functions as a decoy receptor for N-Glycolylneuraminic acid-binding influenza A viruses (IAVs). This product is supplied as a white to off-white powder with a purity of 99.76% confirmed by HPLC analysis.
- Nonhuman sialic acid molecule
- Synthesized in pigs
- Functions as a decoy receptor for influenza A viruses
- High purity (99.76% by HPLC)
- Provided as a powder
- Chemical formula C11H19NO10
- Molecular weight 325.27
- CAS number 1113-83-3
Medchemexpress LLC (Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) | 129622-68-0 | 99.32% | 3478.06 | 10 MG
Asn10,Leu11,D-Trp12-pTH-Related Protein (7-34) amide (human, mouse, rat) is a potent PTH-1R antagonist that does not display any partial agonist activity. This product completely blocks the antioxidant effect of PTHrP(1-37) in mouse osteoblast MC3T3-E1 and primary human osteoblasts, confirming PTH1R activation as the main signaling mechanism for the antioxidant effect of PTHrP(1-37).
- Potent PTH-1R antagonist
- Does not display partial agonist activity
- Blocks antioxidant effect of PTHrP(1-37) in osteoblast cells
- For research use only
Apexbio Technology LLC Heparin(Synonyms: Heparin Sodium, Unfractionated Heparin, Sodium Heparin, Heparinic Acid, Liquaemin, Calciparine), 100mg, CAS: 9005-49-6.
Heparin (CAS 9005-49-6) is a highly sulfated glycosaminoglycan known primarily for its anticoagulant properties In biological systems it is stored in granules within specific animal tissues and cells potentially serving defensive roles against pathogens In vitro studies demonstrate that Heparin dose-dependently suppresses granulocyte aggregation and degranulation triggered by FMLP or serum-activated zymosan and specifically blocks FMLP-induced superoxide anion production Additionally in rat models Heparin treatment reduces both the binding affinity and density of angiotensin II receptors on adrenal cells resulting in decreased angiotensin II-stimulated aldosterone secretion Heparin is extensively applied in biomedical research to investigate granulocyte-mediated inflammation and renin-angiotensin system signaling
Heparin, Fisher BioReagents
CAS: 9041-08-1 MDL Number: MFCD00081689
Heparin Sodium (Laboratory), Fisher Chemical
CAS: 9041-08-1 MDL Number: MFCD00081689
6-Chloro-3-indolyl-beta-D-glucuronide cyclohexylammonium salt, 98%, Thermo Scientific™
CAS: 138182-20-4 Molecular Formula: C14H13ClNO7 Molecular Weight (g/mol): 342.71 MDL Number: MFCD00153940 InChI Key: UFBPRKNLSYGHJJ-BYNIDDHOSA-M Synonym: cyclohexanaminium 2s,3s,4s,5r,6s-6-6-chloro-1h-indol-3-yl oxy-3,4,5-trihydroxytetrahydro-2h-pyran-2-carboxylate,salmon-glca,cyclohexylammonium ion 2s,3s,4s,5r,6s-6-6-chloro-1h-indol-3-yl oxy-3,4,5-trihydroxyoxane-2-carboxylate,c14h14clno7.c6h13n,6-chloro-3-indolyl b-d-glucuronide cyclohexyl,6-chloro-3-indolyl beta-d-glucuronide cyclohexylammonium salt,6-chloro-3-indoxyl-beta-d-glucuronic acid, cyclohexylammonium salt PubChem CID: 16211694 IUPAC Name: (2S,3S,4S,5R,6S)-6-[(6-chloro-1H-indol-3-yl)oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid;cyclohexanamine SMILES: O[C@@H]1[C@@H](O)[C@H](OC2=CNC3=CC(Cl)=CC=C23)O[C@@H]([C@H]1O)C([O-])=O
D(+)-Galacturonic Acid Monohydrate 99%, Thermo Scientific™
CAS: 91510-62-2 Molecular Formula: C6H9O7 Molecular Weight (g/mol): 0.00 InChI Key: AEMOLEFTQBMNLQ-DTEWXJGMSA-M Synonym: d-+-galacturonic acid monohydrate PubChem CID: 91872458 IUPAC Name: (2S,3R,4S,5R,6R)-3,4,5,6-tetrahydroxyoxane-2-carboxylate SMILES: *
5-Bromo-4-Chloro-3-Indolyl-β-D-Glucuronide Cyclohexylammonium Salt, MP Biomedicals™
CAS: 18656-96-7 Molecular Formula: C20H26BrClN2O7 Molecular Weight (g/mol): 521.789 InChI Key: JXCKZXHCJOVIAV-CYRSAHDMSA-N Synonym: c14h13brclno7.c6h13n,cyclohexanaminium 2s,3s,4s,5r,6s-6-5-bromo-4-chloro-1h-indol-3-yl oxy-3,4,5-trihydroxytetrahydro-2h-pyran-2-carboxylate,5-bromo-4-chloro-3-indolyl-beta-d-glucuronide cyclohexylammonium salt,cyclohexylammonium ion 2s,3s,4s,5r,6s-6-5-bromo-4-chloro-1h-indol-3-yl oxy-3,4,5-trihydroxyoxane-2-carboxylate,5-bromo-4-chloro-3-indolyl-beta-d-glucuronide cyclohexyl ammonium salt,5-bromo-4-chloro-3-indoxyl-beta-d-glucuronic acid, cyclohexylammonium salt monohydrate PubChem CID: 42609655 IUPAC Name: (2S,3S,4S,5R,6S)-6-[(5-bromo-4-chloro-1H-indol-3-yl)oxy]-3,4,5-trihydroxyoxane-2-carboxylate;cyclohexylazanium SMILES: C1CCC(CC1)[NH3+].C1=CC(=C(C2=C1NC=C2OC3C(C(C(C(O3)C(=O)[O-])O)O)O)Cl)Br
MP Biomedicals, Inc 5-Bromo-4-Chloro-3-Indoyl-β-D-Glucuronide sodium salt, 98%, Molecular biology reagent grade, For TLC analysis, MP Biomedicals™
CAS: 129541-41-9 Molecular Formula: C14H12BrClNNaO7 Molecular Weight (g/mol): 444.594 MDL Number: MFCD00135782 InChI Key: IBLSVGDGSKUDCT-ILIJQVQCSA-M Synonym: x-gluc sodium salt,x-glca sodium salt,5-bromo-4-chloro-3-indolyl beta-d-glucopyranosiduronic acid sodium salt PubChem CID: 53384407 IUPAC Name: sodium;(2R,3S,4S,5S,6S)-6-[(5-bromo-4-chloro-1H-indol-3-yl)oxy]-3,4,5-trihydroxyoxane-2-carboxylate SMILES: C1=CC(=C(C2=C1NC=C2OC3C(C(C(C(O3)C(=O)[O-])O)O)O)Cl)Br.[Na+]
![Gal beta(1-3)[Neu5Ac alpha(2-6)]GlcNAc-beta-pNP 92.0+%, TCI America™](https://assets.fishersci.com/TFS-Assets/CCG/Chemical-Structures/chemical-structure-cas-754954-71-7.jpg-250.jpg)
Gal beta(1-3)[Neu5Ac alpha(2-6)]GlcNAc-beta-pNP 92.0+%, TCI America™
CAS: 754954-71-7 Molecular Formula: C31H45N3O21 Molecular Weight (g/mol): 795.70 MDL Number: MFCD15072169 InChI Key: OQZSJFGKSKBLDR-UHFFFAOYNA-N PubChem CID: 133554203 IUPAC Name: 5-acetamido-2-{[5-acetamido-3-hydroxy-6-(4-nitrophenoxy)-4-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]methoxy}-4-hydroxy-6-(1,2,3-trihydroxypropyl)oxane-2-carboxylic acid SMILES: CC(=O)NC1C(O)CC(OCC2OC(OC3=CC=C(C=C3)[N+]([O-])=O)C(NC(C)=O)C(OC3OC(CO)C(O)C(O)C3O)C2O)(OC1C(O)C(O)CO)C(O)=O
![Gal beta(1-3)[Neu5Ac alpha(2-6)]GalNAc-alpha-pNP 95.0+%, TCI America™](https://assets.fishersci.com/TFS-Assets/CCG/Chemical-Structures/chemical-structure-cas-1316822-90-8.jpg-250.jpg)
Gal beta(1-3)[Neu5Ac alpha(2-6)]GalNAc-alpha-pNP 95.0+%, TCI America™
CAS: 1316822-90-8 Molecular Formula: C31H45N3O21 Molecular Weight (g/mol): 795.70 MDL Number: MFCD20265590 InChI Key: OQZSJFGKSKBLDR-UHFFFAOYNA-N PubChem CID: 133554216 IUPAC Name: 5-acetamido-2-{[5-acetamido-3-hydroxy-6-(4-nitrophenoxy)-4-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]methoxy}-4-hydroxy-6-(1,2,3-trihydroxypropyl)oxane-2-carboxylic acid SMILES: CC(=O)NC1C(O)CC(OCC2OC(OC3=CC=C(C=C3)[N+]([O-])=O)C(NC(C)=O)C(OC3OC(CO)C(O)C(O)C3O)C2O)(OC1C(O)C(O)CO)C(O)=O
Cayman Chemical Androsterone 1g
A covalent inhibitor of PME-1 (IC50 4.2 nM) selectively inhibits PME-1 over 50 other serine hydrolases in MDA-MB-231 and HEK293T cell lysates at 10 M decreases proliferation of Ishikawa cells and migration of ECC-1 endometrial carcinoma cells when used at a concentration of 50 nM